Sculptra (poly-L-lactic acid, or PLLA) and Radiesse (calcium hydroxylapatite, or CaHA) are both FDA-cleared biostimulators that trigger collagen remodeling, but they work through fundamentally different mechanisms and produce distinct timelines and longevity profiles. Understanding those differences is essential for patient selection, revenue modeling, and managing expectations.
Injectables
Sculptra vs Radiesse: Mechanism, Timeline, and Clinical Use Cases for Medspa Owners
Two FDA-cleared biostimulators with distinct mechanisms and patient outcomes—how to choose between PLLA and CaHA for your practice.
